Customization recipes

ggsurvplot() returns a compound object – a list holding the survival curve ($plot), the risk table ($table), the data actually plotted ($data.survplot), and more – and surv_summary() returns a plain data frame with one row per event/censoring time (time, surv, n.risk, n.event, n.censor, strata, …). Because both are ordinary ggplot2 / data-frame objects, a lot of “can survminer do X?” questions are answered by composing on what these already give you rather than by a dedicated argument.

This page collects such recipes. Each is self-contained and uses the lung data set from the survival package.

library(survminer)
library(survival)
library(dplyr)
library(ggplot2)

Dashed curves once few patients remain at risk

Some reporting guidelines ask that a survival curve be drawn with a dashed line beyond the point where few patients remain at risk – for example the guidelines for reporting mortality and morbidity after cardiac valve interventions recommend a dashed line once the number at risk falls below 10% of the initial cohort (survminer issue #559).

surv_summary() carries n.risk per stratum, so you can find, for each curve, the first time it drops below the threshold, split the curve into a solid “dense” part and a dashed “sparse” tail, and draw the two with different linetypes. Repeating the boundary point in the solid part makes the two step segments meet with no gap.

# KM curves that switch solid -> dashed once the number at risk drops below
# `frac` of each group's initial cohort (default 10%).
ggsurv_dashed_below <- function(fit, data, frac = 0.10, ...) {
  ss <- surv_summary(fit, data = data) %>%
    group_by(strata) %>%
    mutate(onset = { s <- n.risk < frac * max(n.risk)
                     if (any(s)) min(time[s]) else Inf },
           phase = ifelse(time >= onset, "sparse", "dense")) %>%
    ungroup()
  # repeat the first sparse point in the solid phase so the two steps join
  bridge <- ss %>% filter(phase == "sparse") %>%
    group_by(strata) %>% slice_min(time, n = 1) %>% ungroup() %>%
    mutate(phase = "dense")

  ggplot(bind_rows(ss, bridge), aes(time, surv, colour = strata)) +
    geom_step(aes(linetype = phase), linewidth = 0.9) +
    geom_point(data = filter(ss, n.censor > 0), shape = 3, size = 2,
               show.legend = FALSE) +
    scale_linetype_manual(values = c(dense = "solid", sparse = "dashed"),
                          breaks = "sparse",
                          labels = sprintf("< %g%% at risk", 100 * frac),
                          name = NULL) +
    coord_cartesian(ylim = c(0, 1)) +
    labs(x = "Time", y = "Survival probability", ...) +
    theme_survminer()
}
fit <- survfit(Surv(time, status) ~ sex, data = lung)
ggsurv_dashed_below(fit, lung, frac = 0.10) +
  scale_colour_discrete(name = "Sex", labels = c("Male", "Female"))

Each curve turns dashed at its own crossing point. A few adjustments:

  • The threshold is each group’s own initial cohort (max(n.risk) per stratum). To key it to the pooled study size instead, replace max(n.risk) with the overall starting n and every curve dashes at the same count.
  • frac is an argument, so the same helper produces the guideline’s 10% cutoff or any other fraction.
  • This rebuilds the line layer to control linetype, so it does not go through ggsurvplot() directly. If you also want the number-at-risk table underneath, build it separately with ggrisktable() on the same fit and stack the two (for example with ggpubr::ggarrange(..., ncol = 1, heights = c(3, 1))).

Step-shaped legend keys

By default the legend key is a straight horizontal line. Some publications draw the key as a small step that echoes the Kaplan-Meier shape (survminer issue #537). ggsurvplot() returns the curve as $plot, whose first layer draws the survival lines, so you can swap that layer’s legend key for a custom step glyph – overriding only the key, leaving the curve drawing untouched.

library(grid)

# Draw the legend key of a ggsurvplot's curves as a small step (stair) that
# echoes the Kaplan-Meier shape, instead of the default straight line.
step_legend_key <- function(p) {
  `%||%` <- function(x, y) if (is.null(x)) y else x   # base R has this since 4.4
  draw_key_step <- function(data, params, size) {
    grid::linesGrob(
      x = c(0, 0.45, 0.45, 1), y = c(0.25, 0.25, 0.7, 0.7),
      gp = grid::gpar(col = data$colour %||% "black",
                      lwd = (data$linewidth %||% data$size %||% 0.75) * .pt,
                      lty = data$linetype %||% 1, lineend = "butt"))
  }
  # the survival curves are the first layer; subclass its geom to override ONLY
  # the legend key, so the curve drawing itself is unchanged
  g <- p$plot$layers[[1]]$geom
  p$plot$layers[[1]]$geom <-
    ggplot2::ggproto(paste0(class(g)[1], "Key"), g, draw_key = draw_key_step)
  p
}
fit2 <- survfit(Surv(time, status) ~ sex, data = lung)
p <- ggsurvplot(fit2, data = lung, palette = c("#E7302A", "#2E43F3"),
                legend.title = "Group", legend.labs = c("High", "Low"))
step_legend_key(p)

Adjust the x/y coordinates inside draw_key_step() to change the step shape (for example a taller riser, or a two-step stair).

Mark the median survival and its confidence interval

surv.median.line = "hv" already drops a line at each group’s median survival. To also show the confidence interval of the median (survminer issue #345), use surv_median(), which returns median, lower and upper per group, and add a horizontal band at survival = 0.5.

add_median_ci <- function(p, fit, y = 0.5) {
  med  <- surv_median(fit)
  # one colour per group, read from the drawn curve layer (no internal helpers)
  b     <- ggplot2::ggplot_build(p$plot)$data[[1]]
  cols  <- b$colour[match(sort(unique(b$group)), b$group)]
  # drop groups whose median is not reached (surv_median() returns NA there)
  keep  <- !is.na(med$median)
  med   <- med[keep, ]
  cols  <- cols[keep]
  p$plot +
    geom_segment(data = med, aes(x = lower, xend = upper, y = y, yend = y),
                 colour = cols, linewidth = 0.9, inherit.aes = FALSE) +
    geom_point(data = med, aes(x = median, y = y),
               colour = cols, size = 2.4, inherit.aes = FALSE)
}
fit3 <- survfit(Surv(time, status) ~ sex, data = lung)
p <- ggsurvplot(fit3, data = lung, palette = c("#E7302A", "#2E43F3"),
                surv.median.line = "hv",
                legend.labs = c("Male", "Female"), legend.title = "Sex")
p$plot <- add_median_ci(p, fit3)
p

The horizontal bar spans the 95% CI of the median survival time (surv_median()’s lower/upper); the point marks the median itself. A group whose survival never drops to 0.5 has no median (surv_median() returns NA), so it is simply left without a bar.

Plot math (expressions) in the legend

legend.labs = c(expression(...)) alone does not render as math, and + does not apply to the compound ggsurvplot object. Add the scale to $plot (a plain ggplot) instead, supplying the same palette so the colours are unchanged (survminer issue #350).

pal <- c("#E7302A", "#2E43F3")
p <- ggsurvplot(fit3, data = lung, palette = pal, legend.title = "Group")
p$plot <- p$plot +
  scale_colour_manual(values = pal,
                      labels = c(expression(x^2 ~ y^2), expression(alpha[i] >= beta)),
                      name = "Group")
p

(The “Scale for colour is already present” message is expected – we are replacing survminer’s default colour scale with one that carries the math labels.)

With a risk table (risk.table = TRUE), the table’s strata labels are a separate discrete y-axis, so they keep the raw sex=1 / sex=2 names unless you relabel them too. Carry the same expressions to $table with scale_y_discrete(). The table lists the strata top-to-bottom but the discrete y-axis orders its breaks bottom-to-top, so pass the labels reversed to keep each label on its own row:

math.labs <- c(expression(x^2 ~ y^2), expression(alpha[i] >= beta))
p <- ggsurvplot(fit3, data = lung, palette = pal, risk.table = TRUE,
                legend.title = "Group")
p$plot  <- p$plot  +
  scale_colour_manual(values = pal, labels = math.labs, name = "Group")
p$table <- p$table + scale_y_discrete(labels = rev(math.labs))
p

One shared legend across a grid of plots

Several separate survival analyses that use the same grouping are often shown in a grid with a single common legend (survminer issue #340). Pull each ggsurvplot’s $plot and arrange them with ggpubr::ggarrange(), which draws one shared legend and keeps every panel the same size.

colon2  <- colon[!is.na(colon$sex), ]
subsets <- split(colon2, colon2$extent)
subsets <- subsets[sapply(subsets, nrow) > 30]
subsets <- subsets[seq_len(min(4, length(subsets)))]

plots <- lapply(names(subsets), function(nm) {
  d   <- subsets[[nm]]
  fit <- survfit(Surv(time, status) ~ sex, data = d)
  ggsurvplot(fit, data = d, legend.title = "Sex",
             legend.labs = c("Male", "Female"), title = paste("extent", nm))$plot
})

ggpubr::ggarrange(plotlist = plots, ncol = 2, nrow = 2,
                  common.legend = TRUE, legend = "bottom")

Risk table under Cox-adjusted survival curves

Cox-model adjusted curves are drawn with survfit(coxph_fit, newdata = ...), one curve per covariate profile. Asking for risk.table = TRUE there gives a single pooled row, because those predicted curves have no per-group number at risk – the profiles are hypothetical covariate combinations, not subject groups (survminer issue #231).

When the profiles correspond to a real grouping variable (here sex), the meaningful at-risk counts are the Kaplan-Meier ones for that variable. Build them with ggrisktable() from a KM fit and drop them into the compound object’s $table slot, matching legend.labs and sharing an xlim so the two panels line up:

km.fit  <- survfit(Surv(time, status) ~ sex, data = lung)
res.cox <- coxph(Surv(time, status) ~ age + sex + ph.ecog, data = lung)
sex_df  <- with(lung, data.frame(sex = c(1, 2),
                                 age = mean(age, na.rm = TRUE), ph.ecog = c(1, 1)))
fit <- survfit(res.cox, newdata = sex_df)

# note: a survfit() from a coxph fit carries no data, so pass `data =` explicitly
cox.surv <- ggsurvplot(fit, data = sex_df, conf.int = TRUE,
                       legend.labs = c("sex=1", "sex=2"))
cox.surv$table <- ggrisktable(km.fit, data = lung, color = "strata",
                              legend.labs = c("sex=1", "sex=2"),
                              xlim = c(0, max(fit$time)))
print(cox.surv, risk.table.height = 0.28)

Be careful with the meaning: the table is the Kaplan-Meier number at risk for the grouping variable, not an at-risk count for the model-based adjusted curves (adjusted curves are expectations for hypothetical profiles and have no literal number at risk). It is honest only when each newdata row is a real subgroup of the data (e.g. sex = 1 / sex = 2); for arbitrary covariate combinations there is no per-profile risk table and this overlay would mislead.

Risk table under ggadjustedcurves()

ggadjustedcurves() now takes a risk.table argument directly (survminer issue #286): ggadjustedcurves(fit, variable = "sex", data = data, risk.table = TRUE) draws the Kaplan-Meier number-at-risk table for the grouping variable below the adjusted curves (computed on the model’s complete cases, with a title that makes the Kaplan-Meier nature explicit) and returns a ggsurvplot object. The recipe below shows the manual equivalent, which is still useful when you want finer control over the two panels than the built-in arguments give: build a normal Kaplan-Meier ggsurvplot() (which comes with a correctly aligned number-at-risk table for the grouping variable) and swap its $plot for the adjusted-curves plot, matching palette, xlim and x-breaks so the panels line up.

lung2 <- transform(lung, sex = factor(sex, labels = c("Male", "Female")))
pal   <- c("#E7302A", "#2E43F3")
xmax  <- max(lung2$time, na.rm = TRUE)

# a KM ggsurvplot -> aligned curve + number-at-risk table by group
km.surv <- ggsurvplot(survfit(Surv(time, status) ~ sex, data = lung2), data = lung2,
                      risk.table = TRUE, palette = pal,
                      legend.labs = c("Male", "Female"), legend.title = "Sex",
                      break.time.by = 250, xlim = c(0, xmax))

# Cox-adjusted curves (a plain ggplot); match palette / xlim / breaks
res.cox <- coxph(Surv(time, status) ~ sex + age + ph.ecog, data = lung2)
adj <- ggadjustedcurves(res.cox, variable = "sex", data = lung2, palette = pal) +
  coord_cartesian(xlim = c(0, xmax)) +
  scale_x_continuous(breaks = seq(0, xmax, 250)) +
  labs(x = "Time", y = "Adjusted survival probability") +
  guides(colour = guide_legend("Sex"), fill = guide_legend("Sex")) +
  theme_survminer()

# swap the KM curve for the adjusted curve; keep the aligned KM risk table
km.surv$plot <- adj
print(km.surv, risk.table.height = 0.26)

The same honesty caveat applies: the table is the KM number at risk for the grouping variable, not for the adjusted curves, and is meaningful only when the adjustment variable is a real group.

Single event and a number-at-risk table for competing risks

For a cmprsk::cuminc() competing-risks fit, two common requests are to plot only the event of interest (dropping the competing events) and to add a number-at-risk table underneath (survminer issue #223). Both compose from the cuminc object and a companion survfit(): the cumulative-incidence estimates (and their variance) for the event of interest come straight out of cuminc, and the number at risk – subjects still event-free and under observation, the usual convention for a competing-risks figure – is the n.risk of a survfit() that treats any event as the endpoint.

library(cmprsk)

# competing-risks data: event 1 = PCM (of interest), 2 = death (competing)
mg <- transform(mgus2,
                etime = ifelse(pstat == 1, ptime, futime),
                event = ifelse(pstat == 1, 1, 2 * death))
pal <- c("#E7302A", "#2E43F3"); xmax <- max(mg$etime); eoi <- "1"

ci <- cuminc(mg$etime, mg$event, group = mg$sex)

# cumulative incidence of the event of interest, per group, with 95% CI bands
comps <- names(ci)[grepl(paste0(" ", eoi, "$"), names(ci))]
cif <- do.call(rbind, lapply(comps, function(nm) {
  d <- as.data.frame(ci[[nm]][c("time", "est", "var")])
  d$group <- sub(paste0(" ", eoi, "$"), "", nm); d
}))
cif$lower <- pmax(0, cif$est - 1.96 * sqrt(cif$var))
cif$upper <- pmin(1, cif$est + 1.96 * sqrt(cif$var))

p_cif <- ggplot(cif, aes(time, est, colour = group, fill = group)) +
  geom_ribbon(aes(ymin = lower, ymax = upper), alpha = 0.15, colour = NA) +
  geom_step(linewidth = 0.9) +
  scale_colour_manual(values = pal) + scale_fill_manual(values = pal) +
  scale_x_continuous(breaks = seq(0, xmax, 60)) +
  coord_cartesian(xlim = c(0, xmax), ylim = c(0, 1)) +
  labs(x = "Time (months)", y = "Cumulative incidence of PCM") +
  guides(colour = guide_legend("Sex"), fill = guide_legend("Sex")) +
  theme_survminer()

# number-at-risk table: survfit on "any event" gives the event-free at-risk count
km.surv <- ggsurvplot(survfit(Surv(etime, event > 0) ~ sex, data = mg), data = mg,
                      risk.table = TRUE, palette = pal, legend.labs = c("F", "M"),
                      legend.title = "Sex", break.time.by = 60, xlim = c(0, xmax))
km.surv$plot <- p_cif                       # keep the aligned number-at-risk table
print(km.surv, risk.table.height = 0.26)

To pick a different event of interest, change eoi (the numeric fstatus code as a string). The confidence bands use cuminc’s var; note the at-risk counts are the standard event-free-under-observation convention, not a competing-risks weighted count.

Forest plot of several univariate Cox models

ggforest() draws one fitted model. For the common screening step of showing the hazard ratio from a separate univariate Cox model for each candidate covariate on one forest plot (survminer issues #459, #310), fit one model per covariate, collect the HR / 95% CI / p from each, and draw the forest with geom_pointrange() on a log scale.

d <- lung
d$sex     <- factor(d$sex, labels = c("Male", "Female"))
d$ph.ecog <- factor(d$ph.ecog)
vars <- c("sex", "age", "ph.ecog", "wt.loss")   # candidate covariates

# one univariate Cox model per covariate -> HR, 95% CI, p (one row per coefficient)
uni <- do.call(rbind, lapply(vars, function(v) {
  s <- summary(coxph(reformulate(v, response = "Surv(time, status)"), data = d))
  data.frame(variable = v, term = rownames(s$conf.int),
             HR    = s$conf.int[, "exp(coef)"],
             lower = s$conf.int[, "lower .95"],
             upper = s$conf.int[, "upper .95"],
             p     = s$coefficients[, "Pr(>|z|)"], row.names = NULL)
}))
# row label: variable name, plus the factor level for multi-level terms
level <- mapply(function(v, t) sub(paste0("^", v), "", t), uni$variable, uni$term)
uni$label <- ifelse(level == "", uni$variable, paste0(uni$variable, ": ", level))
uni$label <- factor(uni$label, levels = rev(uni$label))

ggplot(uni, aes(HR, label)) +
  geom_vline(xintercept = 1, linetype = "dashed", colour = "grey50") +
  geom_pointrange(aes(xmin = lower, xmax = upper)) +
  geom_text(aes(label = sprintf("%.2f (%.2f-%.2f)", HR, lower, upper)),
            vjust = -0.8, size = 3) +
  scale_x_log10() +
  labs(x = "Hazard ratio (95% CI, log scale)", y = NULL,
       title = "Univariate Cox regression") +
  theme_survminer()

Each row is its own univariate model (not a single multivariable fit); a multi-level factor contributes one row per level. Swap in a multivariable ggforest(coxph(Surv(time, status) ~ ., data = ...)) when you want one adjusted model instead.

A related but different question — the hazard ratio of one covariate across several models (e.g. crude vs. adjusted, or as covariates are added) — is answered directly by ggforest_models(), which puts one model per row for a single shared term.

Smooth parametric (survreg / Weibull) survival curves

A survreg() accelerated-failure-time fit predicts a smooth survival curve; feeding its predictions to ggsurvplot() as a data frame draws them as a step function by default. Use surv.geom = geom_line to draw the curve as a smooth line instead (survminer issue #276). A survreg curve is only defined once the covariates are fixed, so choose the profile(s) to draw:

# a parametric (Weibull) AFT model with a covariate
wb <- survreg(Surv(time, status) ~ sex, data = lung)

# predict(type = "quantile", p = s) returns the time at which survival = 1 - s,
# i.e. the inverse of the fitted survival function; pick the profiles to show.
s    <- seq(0.01, 0.99, by = 0.01)
prof <- data.frame(sex = c(1, 2))
pred <- predict(wb, newdata = prof, type = "quantile", p = s)   # rows = profiles
wbdf <- data.frame(
  time   = as.vector(t(pred)),
  surv   = rep(1 - s, times = nrow(prof)),
  strata = factor(rep(c("sex=1", "sex=2"), each = length(s))),
  upper  = NA, lower = NA, std.err = NA          # a model curve carries no CI band
)

pal <- c("#E7302A", "#2E43F3")
# surv.geom = geom_line -> smooth line, not a step; conf.int = FALSE is required.
ggsurvplot(wbdf, conf.int = FALSE, surv.geom = geom_line, palette = pal,
           legend.title = "Weibull", legend.labs = c("sex=1", "sex=2"))

To judge how well the parametric model fits, overlay the curves (dashed) on the empirical Kaplan-Meier:

km <- ggsurvplot(survfit(Surv(time, status) ~ sex, data = lung), data = lung,
                 palette = pal, legend.labs = c("sex=1", "sex=2"))
km$plot + geom_line(data = wbdf, aes(time, surv, colour = strata),
                    linetype = "dashed", linewidth = 1)

The curve is the model’s prediction at the covariate profile you choose – for a multi-covariate model, fix the other covariates in newdata and decide which one indexes the curves. It is a deterministic parametric fit, not an empirical estimate, so it has no confidence band (upper/lower are NA and conf.int = FALSE is required). For a Weibull fit over the Kaplan-Meier with built-in confidence bands, ggflexsurvplot() (on a flexsurv::flexsurvreg() model) is an alternative.

Subgroup-analysis forest (treatment effect within subgroups)

ggforest() draws the coefficients of a single fitted model, so it cannot produce a subgroup-analysis forest – the effect of a treatment estimated within each subgroup, with an interaction test (survminer issues #271, #366). Build it by fitting the model within each subgroup, collecting the hazard ratios, and adding the treatment-by-subgroup interaction p-value:

# a 2-arm treatment and a few subgroup variables, all coded as factors
d <- subset(colon, etype == 2 & rx %in% c("Obs", "Lev+5FU"))
d$rx     <- factor(d$rx, levels = c("Obs", "Lev+5FU"))
d$Sex    <- factor(d$sex, labels = c("Female", "Male"))
d$Age    <- factor(ifelse(d$age >= 60, ">=60", "<60"), levels = c("<60", ">=60"))
d$Differ <- factor(d$differ, labels = c("well", "moderate", "poor"))
subgroups <- c("Sex", "Age", "Differ")
resp <- "Surv(time, status)"

# treatment HR within one subset; NA if a treatment arm is missing (unstratifiable)
hr_in <- function(sub) {
  if (nlevels(droplevels(sub$rx)) < 2) return(c(NA, NA, NA))
  tryCatch(withCallingHandlers(
    summary(coxph(Surv(time, status) ~ rx, data = sub))$conf.int[1, c(1, 3, 4)],
    warning = function(w) invokeRestart("muffleWarning")),
    error = function(e) c(NA, NA, NA))
}

# overall effect, then each subgroup's levels + its interaction p-value
overall <- summary(coxph(Surv(time, status) ~ rx, data = d))$conf.int[1, c(1, 3, 4)]
tab <- data.frame(subgroup = "Overall", level = "", HR = overall[1],
                  lower = overall[2], upper = overall[3], p.int = NA_real_)
for (sg in subgroups) {
  a <- anova(coxph(reformulate(c("rx", sg), response = resp), data = d),
             coxph(reformulate(paste0("rx*", sg), response = resp), data = d))
  pint <- a[2, grep("^P", colnames(a))]          # treatment x subgroup LRT p-value
  for (lv in levels(d[[sg]])) {
    est <- hr_in(droplevels(d[d[[sg]] == lv, ]))
    tab <- rbind(tab, data.frame(subgroup = sg, level = lv, HR = est[1],
                 lower = est[2], upper = est[3], p.int = pint))
  }
}

# lay out rows: Overall, then a bold header per subgroup with its levels below
rows <- list(data.frame(label = "Overall", tab[1, c("HR","lower","upper","p.int")],
                        header = FALSE))
for (sg in subgroups) {
  rows <- c(rows, list(data.frame(label = sg, HR = NA, lower = NA, upper = NA,
                       p.int = tab$p.int[tab$subgroup == sg][1], header = TRUE)))
  lv <- tab[tab$subgroup == sg, ]
  rows <- c(rows, list(data.frame(label = paste0("   ", lv$level), HR = lv$HR,
                       lower = lv$lower, upper = lv$upper, p.int = NA, header = FALSE)))
}
pl <- do.call(rbind, rows)
pl$y <- factor(rev(seq_len(nrow(pl))))             # first row on top
f2 <- function(v, k = 2) ifelse(is.na(v), "", formatC(v, format = "f", digits = k))
pl$hr.txt <- ifelse(is.na(pl$HR), "",
                    sprintf("%s (%s-%s)", f2(pl$HR), f2(pl$lower), f2(pl$upper)))
pl$p.txt  <- ifelse(is.na(pl$p.int), "", paste0("p-int ", f2(pl$p.int, 3)))
xmin <- min(pl$lower, na.rm = TRUE); xmax <- max(pl$upper, na.rm = TRUE)

ggplot(pl, aes(HR, y)) +
  geom_vline(xintercept = 1, linetype = "dashed", colour = "grey60") +
  geom_pointrange(aes(xmin = lower, xmax = upper), na.rm = TRUE, size = 0.4) +
  geom_text(aes(x = xmin / 5, label = label), hjust = 0, size = 3,
            fontface = ifelse(pl$header, "bold", "plain")) +
  geom_text(aes(x = xmax * 1.6, label = hr.txt), hjust = 0, size = 3, na.rm = TRUE) +
  geom_text(aes(x = xmax * 4.2, label = p.txt), hjust = 0, size = 3,
            fontface = "italic", na.rm = TRUE) +
  scale_x_log10(breaks = c(0.25, 0.5, 1, 2), limits = c(xmin / 5, xmax * 14)) +
  labs(x = "Hazard ratio (Lev+5FU vs Obs, 95% CI, log scale)", y = NULL,
       title = "Treatment effect by subgroup") +
  theme_classic() +
  theme(axis.text.y = element_blank(), axis.ticks.y = element_blank(),
        axis.line.y = element_blank(), plot.title = element_text(hjust = 0.5))

The honest inference is the interaction p-value – does the treatment effect differ across a subgroup’s levels? – not whether an individual subgroup’s HR is “significant”; subgroup analyses are exploratory and multiplicity-prone. Code the subgroup variables as factors, and watch small subgroups: a level with few events (here well, a wide interval) is unstable, and a level missing a treatment arm is dropped rather than plotted. This is a different question from one HR per level of a predictor – for that, just make the predictor a factor and use ggforest().

Compare parametric distributions against the Kaplan-Meier

ggflexsurvplot() overlays one fitted parametric model on the Kaplan-Meier. To compare several distributions and pick the best-fitting family (survminer issue #183), fit each with flexsurv::flexsurvreg(), extract its survival curve, and overlay them on the empirical KM:

library(flexsurv)

# empirical KM (marginal) as the reference: a fixed neutral colour, so only the
# distribution names appear in the legend
km <- ggsurvplot(survfit(Surv(time, status) ~ 1, data = lung), data = lung,
                 conf.int = TRUE, color = "grey50")

# fit several parametric families and extract each fitted survival curve
dists <- c("weibull", "lognormal", "gengamma")
curves <- do.call(rbind, lapply(dists, function(dd) {
  fit <- flexsurvreg(Surv(time, status) ~ 1, data = lung, dist = dd)
  s <- summary(fit, type = "survival", tidy = TRUE)     # time, est, lcl, ucl
  data.frame(time = s$time, surv = s$est, Distribution = dd)
}))

km$plot +
  geom_line(data = curves, aes(time, surv, colour = Distribution), linewidth = 1) +
  scale_colour_brewer(palette = "Set1") +
  labs(x = "Time", y = "Survival probability", colour = "Distribution")


# formal model selection: lower AIC = better fit
sapply(dists, function(dd)
  AIC(flexsurvreg(Surv(time, status) ~ 1, data = lung, dist = dd)))
#>   weibull lognormal  gengamma 
#>  2311.702  2342.538  2313.380

Judge the fit with AIC() (lower is better – here weibull beats gengamma beats lognormal), not by eye alone. The parametric curves extend the model’s assumptions beyond the observed follow-up (the lognormal’s heavier tail past the last event is model-driven, not data-supported), and the overlay drops each fit’s confidence band for legibility (summary() returns lcl/ucl if you want them). Shown for a marginal ~ 1 fit; a covariate model’s curve is defined only at a fixed covariate profile (newdata), as in the survreg recipe above. For a single distribution with its confidence band, ggflexsurvplot() is the built-in.